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The Role of the Amygdala in Agoraphobia and Panic Disorder
by Stephen Price

There has been a recent focus on the amygdala when it comes to explaining the cause of agoraphobia and panic disorder. There have also been some "new" treatment programs for agoraphobia on the market that are aimed at interrupting a certain function of the amygdala.

So what is this thing called the amygdala and is it really important to recovery from agoraphobia and panic disorder?

The amygdala is a small structure located deep inside the brain of both humans and animals. It plays a significant role in panic disorder and agoraphobia because it houses the body's fear response (or the "fight or flight" response - read Anatomy of a Panic Attack for more details).

Neuroscientists tell us that when the body is confronted by a perceived threat, danger signals are sent to two places in the brain:

1) The cerebral cortex
2) The amygdala

The cerebral cortex houses cognitive functions of the brain. The signal sent to the cerebral cortex is sent in the form of information about the threat. The information about the perceived threat is analyzed cognitively in the cerebral cortex. In other words, this is the part of the brain you use to think conscious thoughts.

The amygdala, which houses the fear response, is more involuntary. When danger signals are sent to the amygdala, it sets off the "fight or flight" response to prepare the body to respond to the threat. It does this without you having to even think.

Two factors make the amygdala powerful in causing panic attacks:

1) The amygdala creates indelible (permanent) memories and associations, or so neuroscientists believe.

2) The amygdala activates the fear response faster than the cerebral cortex can analyze the information about the perceived threat.

The implications of agoraphobia research so far on the amygdala is that therapies for panic disorders and agoraphobia are needed that offer the sufferer ways to gain cognitive control over the fear response activated by the amygdala.

If you can train yourself to interrupt the amygdala's fear response with cognitions (thoughts), then you are on your way to short circuiting panic attacks and overcoming agoraphobia and panic disorder.

But so far, the research on the amygdala has not led to any sure-fire quick fix for agoraphobia or panic disorder (though some may make this claim).

Cognitive therapy is nothing new. It has been on the market for agoraphobia for a long time. Plenty of research has shown various forms of cognitive therapy to be effective for agoraphobia, but it takes hard work and discipline to use successfully. And new forms of cognitive therapy that are more effective at interrupting the fear response from the amygdala may need to be developed.

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